NEW DRUG TARGETS. “The principal free D-amino acids found in significant amount in animal tissues are D-Ala, D-serine (D-Ser), and D-aspartate (D-Asp). In particular, D-Ser was detected predominantly in the mammalian brain…the human brain contains endogenous D-Ser and D-Asp, which are likely to act as modulators of neurotransmission.”
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