linkedin post 2016-03-21 05:45:09

SILENCED. “Transcription of HERV-K and other HERV elements is usually suppressed by epigenetic factors such as DNA methylation and heterochromatin-silencing by histone modifications. During tumorigenesis (and also, presumably, in other poorly understood situations) this epigenetic control can be partially or selectively weakened and particular retroviral promoters become able to vigorously activate the transcription of cellular genes.”

http://journal.frontiersin.org/article/10.3389/fonc.2013.00246/full

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