OPEN INNOVATION. “Pathogens as biological ‘systems’: open, robust, modular, and stochastic. Intracellular pathogens can be viewed as the ultimate open system: they are constantly interacting with the infected cell and modulating both the host and the pathogen so as to establish a viable physical/temporal niche. These organisms typically exhibit specific auxotrophies, relying on host metabolic processes for essential nucleotides, amino acids, lipids, sugars, vitamins, etc.”
https://lnkd.in/eusM5UA