DUAL PURPOSE. “In addition to their role in evolution and disease, Alus have clearly been genetically “repurposed” to play many vital roles in gene development, RNA editing, gene regulation, and microRNA regulation. As a race, humans owe a debt of gratitude to this 300 bp piece of DNA that has copied itself over a million times in our genomes. Without it, we would look much more like our mammalian primate and non-primate relatives.”
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