DANGER SENTINEL. “Traditionally, innate immunity has been viewed as the first line of defense discriminating “self” (e.g., host proteins) from “nonself” (e.g., microorganisms). However, emerging literature suggests that innate immunity actually serves as a sophisticated system for sensing signals of “danger,” such as pathogenic microbes or host-derived signals of cellular stress, while remaining unresponsive to nondangerous motifs, such as normal host molecules, dietary antigens, or commensal gut flora.”
https://lnkd.in/e4CzrPZ
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022