SMALL CHANGES, VAST EFFECTS. “Alternative splicing regulates the localization of proteins, their enzymatic properties and their interaction with ligands. In most cases, changes caused by individual splicing isoforms are small. However, cells typically coordinate numerous changes in ‘splicing programs’, which can have strong effects on cell proliferation, cell survival and properties of the nervous system.”
http://www.sciencedirect.com/science/article/pii/S0378111912009791
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022