CONSERVED EXONS. “Interestingly, tissue-regulated exons associated with the highest rates of disordered amino acids also tended to be the most highly conserved. For example, 63% of the 101 most disordered human brain, skeletal, and or heart-differentially spliced exons are also alternatively spliced in mouse, whereas only 31% of the least disordered 81 exons differentially spliced in these tissues were detected as alternatively spliced exons.”
http://www.sciencedirect.com/science/article/pii/S1097276512004820
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022