FIRST BIG CONCEPT UNLEASHED. “The discovery of RXR and its ligand resulted in the genesis of two prodigious concepts in the nuclear receptor field. First, in revealing the existence of a previously unknown signaling pathway, it provided a proof of principle that precipitated a wave of research aimed at linking other orphan receptors to specific ligands.” (RXR = retinoid receptor).
https://lnkd.in/dXjCCgQ