RADIAL TO BILATERAL SHIFT. “The current model, mostly derived from A. majus, involves sequential steps leading to a shift from radial to bilateral symmetry in the petal whorl: (1) CYC2-like genes are dorsally restricted; (2) CYC2-like genes up-regulate RADIALIS (RAD) in the dorsal region; (3) RAD negatively regulates weakly ubiquitous DIVARICATA (DIV), leaving DIV to localize in the outer epidermis of only the ventral region; and (4) DIV possibly up-regulates AmMYBML1, which functions in forming trichomes, conical cells, and the hinge of the ventral petal.”
http://onlinelibrary.wiley.com/doi/10.1111/nph.13198/full