HYBRID ORGANISMS. “We now know that all multicellular eukaryotes are actually functional composites, holobionts, composed of more prokaryotic cells than eukaryotic cells and expressing more prokaryotic genes than eukaryotic genes. A full understanding of the biology of “individual” eukaryotes will now depend on an understanding of their associated microbiomes.”
https://standardsingenomics.biomedcentral.com/articles/10.1186/s40793-016-0180-8