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linkedin post 2021-11-20 05:34:57

POSITIVE IMPACT. “However, the hypermutator subpopulation has increased evolvability because it has a much higher per-capita chance of producing the next highly beneficial mutation, or multiple beneficial mutations, than a non-mutator competitor (Fig. 3a). Thus, despite their slight fitness costs, hypermutators can sometimes hitchhike to fixation with the beneficial mutations that they generate.”

https://www.nature.com/articles/nrg3564

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