Month: September 2022

NONCODING RNAs. "Their work provides circumstantial evidence that small non-coding RNAs called microRNAs (miRNAs)—small molecules that consist of about 22 nucleotides—are a major causal factor for structural change and increasing complexity among organisms." https://lnkd.in/eNHFjJ8 View in LinkedIn

RNA REGULATORY GENES. "The percentage of coding for such proteins in the human 3 billion base pairs is only 1.5%, however. All the other DNA contains non-coding RNAs (up to 45%) and non-coding areas with unknown functions (55%) which I suggest represent non-coding RNAs of regulatory functions. This means in all organisms we can find the genotype and the encoded phenotype." https://lnkd.in/eg6uePF View in LinkedIn

GEMOME AND EPIGENETICS. "The genotype contains the whole blueprint for the phenotype. The interesting thing is that the variety of parts that constitute the phenotype throughout its developmental stages as well as its regulation is coded in the genotype together with epigenetic markings." https://lnkd.in/eg6uePF View in LinkedIn

"EPIGENETICS is an effective tool for expanding the informational content of a given nucleotide sequence with multiple meanings/functions representing experiences in historical contexts in real-life worlds." https://lnkd.in/eg6uePF View in LinkedIn

DYNAMIC INPUT. "We know that epigenetic markings silence or increase the various outcomes of genetic information: a good example is the phenotype of brain organs and their synaptic neuronal networks. This means a single genotype may have several reading patterns which result in slightly different phenotypes." https://lnkd.in/eg6uePF View in LinkedIn

A million bottles a minute: world's plastic binge 'as dangerous as climate change' https://www.theguardian.com/environment/2017/jun/28/a-million-a-minute-worlds-plastic-bottle-binge-as-dangerous-as-climate-change?CMP=Share_iOSApp_Other View in LinkedIn

MICRO-RNAs AND COMPLEXITY. "In the evolutionary context, it is noteworthy that expansions of miRNAs seem to be associated with body-plan innovations and other phenotypic changes in bilaterians and vertebrates. They may therefore have significantly contributed to phenotypic evolution in animals." https://lnkd.in/dDg9xVY View in LinkedIn

FIRST GENOMIC EVOLUTION DRIVER. "Three crucial drivers of genomic evolution. The first drivers are protein-encoding genes themselves—which Berjerano described as the ‘big beasts' of evolution—around which the rest of the genome revolves." https://lnkd.in/eNHFjJ8 View in LinkedIn

SECOND GENOMIC EVOLUTION DRIVERS "are miRNAs, which regulate the activity of messenger RNAs (mRNA) after transcription." https://lnkd.in/eNHFjJ8 View in LinkedIn

THIRD GENOMIC EVOLUTION DRIVERS "are other non-coding regions of the genome that make up the so-called cis-regulatory network, which controls the production of mRNA and thereby of proteins according to factors such as cell type or environmental conditions." https://lnkd.in/eNHFjJ8 View in LinkedIn