Month: September 2022

DIVISION REPRESSION. "The boundary zone itself expresses a specific set of transcription factors that locally repress cell division. Mutations in these regulators or their downstream targets cause organ fusion as well as alterations in organ development and phyllotactic patterning and such developmental defects can occur during embryogenesis, lateral organ formation and even leaf margin serration." https://lnkd.in/dD4GcAS View in LinkedIn

BOUNDARY FORMATION. "Because of the diversity of developmental stages influenced by what appears to be a conserved process, we hypothesize that a conserved ‘boundary formation gene regulatory networks’ plays a central role in boundary formation at different hierarchies during plant development." https://lnkd.in/dD4GcAS View in LinkedIn

REDUNDANCY. "This boundary formation network is a robust developmental network: redundant yet specialized. In addition to maintaining redundancy in its conserved core genes, spatially and temporally regulated network regulators, such as the miRNA164 genes, provide the network with developmental robustness, enabling it to function in the face of various developmental perturbations." https://lnkd.in/dD4GcAS View in LinkedIn

BOUNDARY GENES. "Various ‘boundary genes’ function to ensure proper organ initiation and placement across the shoot apex; for example, BLADE ON PETIOLE 1 and BLADE ON PETIOLE 2 (BOP1/2) transcription factors are expressed in the meristem-to-organ boundary and at the base of lateral organs to enable proper primordia development." https://lnkd.in/dD4GcAS View in LinkedIn

CONSERVED GENE NETWORK. "In summary, while connation or adnation may be mediated by different gene expression patterns and gene products, both spatially and temporally, an underlying common gene regulatory network may function as a conserved boundary-specification mechanism." https://lnkd.in/dD4GcAS View in LinkedIn

BROAD FUNCTIONALITY. "In addition to being evolutionarily conserved, the organ boundary gene regulatory network is likely to be conserved within a given species, such that the same gene regulatory network is used for the process of boundary formation between the shoot apical meristems and lateral organs and among lateral organ primordia whether in the vegetative or reproductive state." https://lnkd.in/dD4GcAS View in LinkedIn

FINE TUNING. "By having a redundant gene regulatory network that is regulated by upstream elements that can be expressed in spatially and temporally restricted manners, the boundary gene regulatory network can be evoked (or not) to differentially regulate the separation or fusion of individual organ primordia throughout the life of the plant. The presence of miRNA-based regulators in this robust pathway further contributes to the ability to fine-tune organ morphogenesis." https://lnkd.in/dD4GcAS View in LinkedIn

CHIMERIC ORGANS. "In addition to resulting in organ fusion, boundary mutations can also cause primordia to incorporate cells from whorls that are normally distinct, creating chimeric organs. Such chimeras could provide the basis for novel organ formation, such as coronas in Narcissus or Asclepias." https://lnkd.in/dD4GcAS View in LinkedIn

GENETIC BRICOLAGE. "An investigation of the many forms of fusion across flowers may demonstrate the importance of a genetic ‘bricolage’ involving both reuse (cooption) and reassembly of ancestral genetic networks." https://lnkd.in/dD4GcAS View in LinkedIn

"ADAPTATION can be defined as the heritable change in the traits of a system in order to maintain or improve fitness within novel environments. Evolvability is the propensity for a system to discover adaptations (= heritable beneficial phenotypes). Thus the ability to discover distinct heritable phenotypes and the ability to transform novel traits into useful innovations during development within a particular environment are essential elements of adaptation." https://lnkd.in/dD4GcAS View in LinkedIn