Month: September 2022

SKIN DEATH. "A process involving programmed cell death which we are all familiar with is death of skin cells. The skin is constantly being renewed and this renovation involves death of cells in outer layers of the skin. These cells do not die by apoptosis, but by a process called ‘cornication’ or ‘keratinization’ of the outer layers of the epidermis." https://celldeath.files.wordpress.com/2010/11/lopezself_munoz.pdf View in LinkedIn

PLANT Cell Death. "In plants, cell death is part of the normal cycle of the organism. Developmental cell death is observed in many plant tissues, being crucial for instance for senescence of leaves and flowers, formation of pollen and seeds and terminal differentiation of vascular elements. Moreover, plant cells undergo Programmed Cell Death in response to infection." https://celldeath.files.wordpress.com/2010/11/lopezself_munoz.pdf View in LinkedIn

DEATH BY TELOMERE. "A second 'deliberate' mechanism is called replicative senescence or cellular senescence. Metaphorically, a cell may be said to 'count' (with its telomeres) the number of times that it has divided, and after a set number of replications, it languishes and dies. It has been proposed that this mechanism evolved to suppress cancer." https://lnkd.in/dUX_Fna View in LinkedIn

TELOMERE REPLENISHMENT. "Even one-celled organisms count replications, and will die if they don't replenish their telomeres with conjugation (sex)." https://lnkd.in/dUX_Fna View in LinkedIn

SENESCENCE. "Many invertebrates experience replicative senescence, though they never die of cancer." https://lnkd.in/dUX_Fna View in LinkedIn

IMMORTALITY LOST. "Biological evolution acts to increase the fitness and performance of species evolving in successive generations. From this perspective it was difficult to understand why natural selection seemed to result in such bizarrely injurious features as senescence and late-life degenerative diseases instead of eternal youth and immortality." https://lnkd.in/dMUQBti View in LinkedIn

DEGENERATION BEYOND SELECTION. “Many manifestations of aging happen after the reproductive period of evolving organisms at ages which are beyond the reach of natural selection." http://longevity-science.org/Evolution.htm View in LinkedIn

DIMINISHED SELECTION WITH AGE. "Mutation accumulation theory: From the evolutionary perspective, aging is an inevitable result of the declining force of natural selection with age." http://longevity-science.org/Evolution.htm View in LinkedIn

DUAL-ACTING GENES. "Antagonistic pleiotropy theory: Late-acting deleterious genes may even be favored by selection and be actively accumulated in populations if they have any beneficial effects early in life." http://longevity-science.org/Evolution.htm View in LinkedIn

LACK OF EVOLUTION. "Interestingly, since the 1950s, no fundamentally new evolutionary theories of aging have been proposed." http://longevity-science.org/Evolution.htm View in LinkedIn