Month: September 2022

GENOME COMPLEXITY ISSUES. "Despite recent developments in genomics it remains unclear why gene content, chromosome number, and genome size vary independently of each other. Is there a tendency for genome size or chromosome number to increase or decrease over time? Does genome size or chromosome number have an adaptive value and, if so, what is that value?" https://lnkd.in/dsqiJD5 View in LinkedIn

NOT A SIMPLE CORRELATION. "The relationship between genomic complexity and the complexity at various levels of the phenotype, from molecular to organismal, is far from being straightforward as it has become clear already in the pre-genomic era." Some relatively simple creatures have much greater genomic complexity than more complex creatures. https://lnkd.in/egqWFZp View in LinkedIn

THE ONION QUESTION. "Why does an onion require five times more of it (the genome) than a human?” https://lnkd.in/eT5V5Xc View in LinkedIn

BEYOND THE ONION. "Importantly, the comparison is not restricted to onions versus humans. It could as easily be between pufferfish and lungfish, which differ by ∼350-fold, or members of the genus Allium, which have more than a 4-fold range in genome size that is not the result of polyploidy." https://lnkd.in/eT5V5Xc View in LinkedIn

STREAMLINING AND OUTSOURCING. Extreme genome reduction in symbiotic bacteria. https://lnkd.in/dx2k-vt View in LinkedIn

REVERSIBLE POLYPLOIDY. "It is immediately apparent that polyploidy is, at least in part, reversible, and that over time it is followed by massive chromosomal rearrangements, reductions in chromosome number, and the large-scale loss of both repetitive sequences and duplicated genes all leading to genome downsizing." https://lnkd.in/eiPytFX View in LinkedIn

REVERSAL OF SPECIALIZATION. "Recently, however, a growing number of studies of specialization indicate that transitions from specialization to generalization are possible." https://lnkd.in/dcsE4uQ View in LinkedIn

DNA FIRST PROPOSITION. "The assertion that organisms are simply DNA's way of producing more DNA has been made so often that it is hard to remember who made it first." https://lnkd.in/duMgVnm View in LinkedIn

DNA MILIEU. "Natural selection does not operate on DNA only through organismal phenotype. Cells themselves are environments in which DNA sequences can replicate, mutate, and so evolve." https://lnkd.in/duMgVnm View in LinkedIn

DNA SELECTIVE PRESSURE. "The only natural selection pressure that DNAs experience directly is the pressure to survive within cells." https://lnkd.in/duMgVnm View in LinkedIn