Month: September 2022

HUMAN TRIALS. "Over the past two years, a handful of companies have sprung up to develop CRISPR-based gene therapy, and Anderson and others say that the first clinical trials of such a treatment could happen in the next one or two years." http://www.nature.com/news/crispr-the-disruptor-1.17673 View in LinkedIn

"CRISPR is the Model T of genetics. The Model T wasn’t the first car, but it changed the way we drive, work, and live. CRISPR has made a difficult process cheap and reliable. It’s incredibly precise. But an important part of the history of molecular biology is the history of editing genes.” http://www.newyorker.com/magazine/2015/11/16/the-gene-hackers View in LinkedIn

"CRISPR works differently: it relies on an enzyme called Cas9 that uses a guide RNA molecule to home in on its target DNA, then edits the DNA to disrupt genes or insert desired sequences. Researchers often need to order only the RNA fragment; the other components can be bought off the shelf. Total cost: as little as $30. “That effectively democratized the technology so that everyone is using it...It's a huge revolution.” http://www.nature.com/news/crispr-the-disruptor-1.17673 View in LinkedIn

REFLECTION. "When I’m ninety, will I look back and be glad about what we have accomplished with this technology? Or will I wish I’d never discovered how it works?” http://www.newyorker.com/magazine/2015/11/16/the-gene-hackers View in LinkedIn

CRISPR. "It could at last allow genetics researchers to conjure everything anyone has ever worried they would—designer babies, invasive mutants, species-specific bioweapons, and a dozen other apocalyptic sci-fi tropes. It brings with it all-new rules for the practice of research in the life sciences." http://www.wired.com/2015/07/crispr-dna-editing-2/ View in LinkedIn