Month: September 2022

"THE CENTRAL DOGMA of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred from protein to either protein or nucleic acid. (Crick 1970). https://lnkd.in/eXBPqD5 View in LinkedIn

SYDNEY BRENNER, while at the Cambridge MRC Unit in 1961 discussed the primary assumption that DNA contains the genetic information for protein synthesis, as do other downstream molecules like mRNA and others. https://lnkd.in/eCSzcsG View in LinkedIn

"DNA is a structure that codes biological information. That is not controversial." https://lnkd.in/e2H4YB4 View in LinkedIn

GENETIC PROGRAM. "Genes contain a program, in a sense analogous to that in computer science." https://lnkd.in/eHPWXiJ View in LinkedIn

INFORMATION IN GENES. "The "sense of “genetic coding” is one of the best-established and least problematic ways of using informational concepts within biology." https://lnkd.in/espyFHA View in LinkedIn

"GENES contain instructions, not descriptions." https://lnkd.in/eHPWXiJ View in LinkedIn

UTILITY IS THE KEY. "Signals by themselves do not usually contain any meaning, i.e., supplying useful patterns, material or energy. Rather, meaning appears only when the agents involved in communication interpret the information." https://lnkd.in/eJc-Z-m View in LinkedIn

SO ENDS the first weekend Fragment about information in biology, which is a central concept today, especially as biology and computers continue to converge, work side by side experimentally, and share a common language and even conceptual framework. View in LinkedIn

DEFECTIVE VIRUS. "In virology, defective interfering particles (DIPs), also known as defective interfering viruses, are spontaneously generated virus mutants in which a critical portion of the particle's genome has been lost due to defective replication." It depends on another virus (a "helper virus") for its replication. https://lnkd.in/ejcrqcC View in LinkedIn

DEFECTIVE INTERFERING PARTICLES "(DIPs) are derived from and associated with their parent virus, and particles are classed as DIPs if they are rendered non-infectious due to at least one essential gene of the virus being lost or severely damaged as a result of the defection." https://lnkd.in/ejcrqcC View in LinkedIn