Month: September 2022

JUNK BEGETS NOVELTY. "There are some indications that noncoding DNA plays a role in the de novo generation of genes." Smile at the reversals of history. https://lnkd.in/euyhznh View in LinkedIn

REPETITIVE INTRONS OF JUNK DNA. "Nearly all genetic and genome editing processes involve RNAs, which in most cases function as a network. Most of the functions are performed, conducted, and regulated by noncoding RNAs, which are encoded in intronic DNA in most cases with repetitive syntax." (Junk used with irony). https://lnkd.in/euyhznh View in LinkedIn

VIRAL MOBILE ELEMENTS. "Noncoding RNAs are similar to all kinds of mobile genetic elements such as LTRs, non- LTRs, SINEs, LINEs, snoRNAs, and snR- NAs, all of persistent viral origin." https://lnkd.in/euyhznh View in LinkedIn

HALF OUR DNA IS VIRAL. "About 8% of the human genome originates from retroviruses and if we measure viral products, almost half the human DNA is viral. A symbiosis of this sort may have led to development of the placenta, and certain key promoters, enhancers and silencers of genes owe their origin to these viruses." Worth repeating endlessly. https://lnkd.in/eZu6_fe View in LinkedIn

SMALL FRACTION. "About 2% of the human genome is transcribed into mature protein-coding RNAs, while the large majority, between 70%–90%, is transcribed into non-protein coding RNAs (ncRNAs). ncRNAs include several types of RNA, exemplified by transfer RNAs (tRNAs), ribosomal RNAs (rRNAs) and small nuclear RNAs (snRNAs), with very well defined function in many cellular processes." https://lnkd.in/ef6MAfH View in LinkedIn

LARGELY UNKNOWN. "Besides these classical ncRNAs, there are various ncRNAs of unknown function, many of which are considered as lncRNAs based on their size greater being than 200 nucleotides. These, apart from the lack of protein-coding potential, have relatively low levels of evolutionary conservation and originate from genes that are usually shorter than protein-coding genes, with fewer exons." (ncRNAs = non-protein coding RNAs; IncRNAs = antisense long non-coding RNAs). http://www.mdpi.com/1422-0067/16/2/3251/htm View in LinkedIn

SYMBIOGENESIS. "Perhaps the best known example of symbiogenesis is the similarly named Endosymbiotic Theory popularized by evolutionary scientist Lynn Margulis. This explanation of how eukaryotic cells evolved from prokaryotic cells is the currently accepted theory in science. Instead of competition, various prokaryotic organisms worked together to create a more stable life for all involved. A larger prokaryote engulfed smaller prokaryotes that became what we now know as various important organelles within a eukaryotic cell." https://lnkd.in/esJqNWw View in LinkedIn

REVOLUTIONARY PHENOMENA. "If symbiogenesis, via symbiosis, creates a new species and therefore extinguishes the formerly independent individuals, then this involves generative DNA text processing in which genetically different gene pools are combined into one DNA text. This is one of the most revolutionary phenomena in biology." https://lnkd.in/eDswHmC View in LinkedIn

SYMBIOGENESIS. "Recombination makes a foreign data set into one’s own, the “non-self” to a “self”, an object of external perception to a subject of internal proprioception." https://lnkd.in/eDswHmC View in LinkedIn

CODING AND NON-CODING. "In the last decade even the significance and indispensable structural function of non-coding RNA becomes more and more interesting. In every case, enzyme proteins competent in text processing carry out these highly differentiated tasks on protein-coding DNA regions with great precision." https://lnkd.in/eDswHmC View in LinkedIn