Month: September 2022

World heritage in the high seas: oceanic wonders explored View in LinkedIn

POWERFUL GENETIC MAKEOVERS. "Recent research shows extensive dynamic DNA remodelling by mobile agents, such as transposons, retroposons, and noncoding RNAs, which are able to cause a wide variety of DNA arrangements, rearrangements, and recombinations." https://lnkd.in/euyhznh View in LinkedIn

MOBILE GENETIC ELEMENTS. "These agents enable complex organisms to integrate several temporal steps and a great variety of coordinated signalling processes in eukaryotic cell replication, fix them in a conserved DNA storage medium, and if necessary, resolve conservation, change, rearrange, or newly construct the whole genomic content and sequence order." https://lnkd.in/euyhznh View in LinkedIn

SWARM SOPHISTICATION. "It is now possible to appreciate how sophisticatedly the competent agents act in the case of endogenous retroviral swarms, that have reached a persistent and nonlytic lifestyle." https://lnkd.in/euyhznh View in LinkedIn

CHALLENGING FORENSICS. "We also know that all related retro-elements share a common genome-editing capacity similar to transposable elements. Nonetheless, it remains difficult to reconstruct how all these DNA-encoded RNA agents reached a persistent status in hundreds, thousands, and tens of thousands of elements." https://lnkd.in/euyhznh View in LinkedIn

RETRO-ELEMENTS. "We only know that they act in a precisely coordinated manner that would be impossible without competent signalling. This includes a strict capacity for self/nonself identification, which is a major asset of RNAs in general and of small nucleolar RNAs in particular." https://lnkd.in/euyhznh View in LinkedIn

PREFERRED HABITAT. "Persistent endogenous agents that are competent in natural genome editing apparently prefer a special kind of habitat characterized as noncoding DNA sectors. They use a syntax mainly consisting of direct or inverted repeats." https://lnkd.in/euyhznh View in LinkedIn

PERSISTENT ENDOGENOUS AGENTS "colonized DNA genomes by inserting their sites beside coding elements; then they use these coding elements for different needs." https://lnkd.in/euyhznh View in LinkedIn

DIVISION OF LABOR. "In the human genome, only 3% of coding regions remain. The remaining 97% serve as a habitat for persistent viral operators that orchestrate a highly sophisticated division of labor. From these regions they can actively regulate coding sequences because they are able to change specific DNA content throughout the genome." https://lnkd.in/euyhznh View in LinkedIn

ENDOGENOUS EDITING AGENTS. "All eukaryotic DNA replication processes share a cut-and-paste process in which noncoding elements, that is, introns, are spliced out; later the remaining exons that code for proteins are combined into a coherent protein-coding content ready for translation." https://lnkd.in/euyhznh View in LinkedIn