linkedin post 2017-07-16 05:40:06

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LOSS OF DIVERSITY. "Species diversity can be lost through two different but potentially interacting extinction processes: demographic decline and speciation reversal through introgressive hybridization. We argue that extinction by speciation reversal may be more widespread than currently appreciated." https://lnkd.in/dPU42hm View in LinkedIn
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linkedin post 2017-07-16 05:45:51

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SO ENDS this first weekend on the reversal of speciation. Although the biological trend is predominantly towards increased specialization to exploit narrower niches, the demonstration that a reversion to generalization occurs bucks the age-old, and wrong, cliche of an inexorable march towards perfect adaptation. Nature is to cunning and plastic to have but a single directionality. Even symmetries may be reversed. View in LinkedIn
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linkedin post 2017-07-17 04:39:29

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HOTSPOT GENE CONVERSION. "One process recognized as a major evolutionary force re-shaping the genomic nucleotide landscape at recombination hotspots, as shown in humans, chimpanzees, mice, yeast, and metazoans, is GC-biased gene conversion (gBGC). In gBGC, the repair of heteroduplex tracts formed during meiotic recombination leads to the non-Mendelian segregation of alleles favoring GC over AT variants." https://lnkd.in/df6FZrB View in LinkedIn
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linkedin post 2017-07-17 04:48:42

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MEIOTIC MUTATIONS. "We present experimental evidence showing that meiosis is an important source of germline mutations. Because sites of meiotic recombination experience recurrent double-strand breaks at hotspots, recombination has been previously suspected to be mutagenic." https://lnkd.in/df6FZrB View in LinkedIn
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linkedin post 2017-07-17 04:51:20

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"GENE CONVERSION, a process of non-reciprocal recombination that can either maintain genetic identity or promote genetic diversity. Gene conversions are initiated by chromosomal double stranded breaks that are subsequently repaired by the strand invasion of a homologous sequence." https://lnkd.in/dmTbDxE View in LinkedIn
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