Year: 2022

KITCHEN OF TEMPLATE PLATTERS. “The protein-coding sequences are templates. They determine which set of proteins the organism has to play with, just as a child knows which pieces of Lego or Meccano she has available for construction. Those parts of the genome are best regarded as a database.” http://rsfs.royalsocietypublishing.org/content/2/1/55 View in LinkedIn

NO BLUEPRINT EXISTS. “Even when we add in the regulatory and non-coding regions, there is no program in the genome in the sense that the sequences could be parsed in the way in which we would analyse a computer program to work out what it is specifying. The reason is that crucial parts of the program are missing.” http://rsfs.royalsocietypublishing.org/content/2/1/55 View in LinkedIn

SO ENDS this first of two weekends with Denis Nobel. Ideas evolve. In recent history, the genome was discovered. In short order, it was sequenced in many species. Then environmental influences were described. And with each step, our understanding of the meaning of the genome has changed. And will continue to do so as new findings occur. View in LinkedIn

REFERENCE FOR TODAY: Are Internal, Death-Promoting Mechanisms Ever Adaptive?" "John W Pepper, Deborah E Shelton, Armin Rashidi, and Pierre M Duran. (This reference refuses to post normally on LI). View in LinkedIn

NO COST TO LONGEVITY. "A recent study of Caenorhabditis elegans reported that selecting for early fecundity did not produce a cost in terms of longevity." View in LinkedIn

CONSENSUS AND EXCEPTIONS. "AP and disposable soma hypotheses are widely accepted as the standard explanations for genetic programs that cause senescence in multicellular organisms. However, there are some results that are in conflict with their predictions." (AP = antagonistic pleiotrophy hypothesis). View in LinkedIn

PRIMARY UNIT OF SELECTION. "A common theme in all the hypotheses discussed above is that the organism is the primary unit of selection." View in LinkedIn

SUICIDE BENEFITS GROUP. "Pea aphids (Acyrthosiphon pisum) that are parasitized by the Braconid wasp Aphidius ervi drop from the host plant, causing their own death. These insects live in groups of close kin, and their death prevents their body from producing parasites that would then attack their siblings. Death therefore increases the individual’s inclusive fitness, or equivalently, increases the fitness of the kin group." View in LinkedIn

ARACHNID SACRIFICE. "Male self-sacrifice”, or apparent male cooperation with female cannibalism, is part of male copulatory behavior in several spider species, and in some insects. One study also reported that males of the spider Argiope aurantia spontaneously die when they copulate." View in LinkedIn

SNUFF FECUNDITY. "In redback spiders, cannibalized males increase their paternity compared to non-cannibalized males, so it is thought that self-sacrifice evolved due to this reproductive advantage. The fitness benefit provided by this behavior raises intriguing possibilities." View in LinkedIn