Year: 2022

FEEDBACK LOOPS. "The circadian oscillator of higher plants comprises transcriptional– translational feedback loops similar to those described earlier for fungal and animal clocks." https://lnkd.in/d_f7kfY View in LinkedIn

CLOCK GENES. "Expression of the LHY and CCA1 mRNA levels oscillates and levels of both transcripts peak shortly after dawn. The LHY and CCA1 proteins also are synthesized rhythmically with a lag of approximately 2 h after their cognate mRNAs. Both transcription factors bind to a promoter element known as the evening element and act to inhibit transcription of evening-specific genes, including TOC1. In the evening, the level of both repressors declines and transcription of the TOC1 gene resumes." https://lnkd.in/d_f7kfY View in LinkedIn

CLOCK CYCLE. "Accumulation of the TOC1 protein at night promotes transcription from the LHY and CCA1 promoters, thus initiating a new cycle." https://lnkd.in/d_f7kfY View in LinkedIn

INTERLOCKING LOOPS. "Evidence is accumulating that the plant circadian clock comprises additional interlocking feedback loops, similar to those described in animal and fungal clocks." https://lnkd.in/d_f7kfY View in LinkedIn

ENTRAINMENT BY PHOTORECEPTORS. "Synchronization of circadian clocks to light–dark cycles (often described as entrainment) is mediated by the action of multiple photoreceptors. In Arabidopsis, this includes at least four of the five phytochromes." https://lnkd.in/d_f7kfY View in LinkedIn

OSCILLATOR ROLE. "In most organisms, effects of light on the clock are mediated by light-induced changes in the level of one of the oscillator components. Plants are unusual in this respect because light affects the oscillator at several levels." https://lnkd.in/d_f7kfY View in LinkedIn

SO ENDS this second of three weekends dedicated to plant clocks. The last weekend shows how the clocks are used to control flowering. The sheer diversity of plant solutions, the modulations on a theme, and the use of quite different molecular strategies to solve clock issues is an Exemplar of the sophistication of these strange creatures called plants, that we still barely understand. View in LinkedIn

EMERGENCE. "Stephen Wolfram was so astonished when he discovered how very complicated results could be obtained with very simple rules that he began a thorough research in the 1980s then published "A New Kind of Science" in 2002. He emphasizes notably the power of CA to experiment on emergence: the apparition of complexity or order, out of simple systems." https://lnkd.in/dN7T9ZC View in LinkedIn

ACCUMULATING COMPLEXITY. "For if there is any purpose legible at all in the millennia of human history, it is in the unflagging persistence with which we add to the complexity of the universe." Except viruses which devolve from complexity to simplicity. The story is a bit more complicated than the simple ascent to complexity. https://lnkd.in/edrARjk View in LinkedIn

CURRENT STATUS. Work continues on Conway’s Game of Life. A sampling of the imaginative projects undertaken, https://lnkd.in/dJ89ZU9 View in LinkedIn