Year: 2022

MOLECULAR SELF-ASSEMBLY. "The formation of molecular crystals, colloids, lipid bilayers, phase-separated polymers, and self-assembled monolayers are all examples of molecular self-assembly. Although self-assembly originated in the study of molecules, it is a strategy that is, in principle, applicable at all size scales." https://lnkd.in/dyqXZ8k View in LinkedIn

NANO-BIOMIMICRY. "Significant progress can be made in the development of nanoscience by transferring concepts found in the biological world into the chemical arena. Central to this mission is the development of simple chemical systems capable of instructing their own organization into large aggregates of molecules through their mutual recognition properties." https://lnkd.in/dkPudC4 View in LinkedIn

NANO-BIOMIMICRY RELIES ON NON-COVALENT BONDS. "The precise programming of these recognition events, and hence the correct assembly of the growing superstructure, relies on a fundamental understanding and the practical exploitation of non-covalent bonding interactions between and within molecules." https://lnkd.in/dkPudC4 View in LinkedIn

TOXIN SELF-ASSEMBLY. "Pore-forming toxins (PFT) are water-soluble proteins that possess the remarkable ability to self-assemble on the membrane of target cells, where they form pores causing cell damage. The incorporation of lipids from the target membrane within the structure of the pore provides a membrane-specific trigger for the activation of a haemolytic toxin." https://lnkd.in/d5kUq7X View in LinkedIn

NANO-SELF ASSEMBLY. "The ability to assemble nanoparticles into well-defined configuration in space is crucial to the development of electronic devices that are small but can contain plenty of information. The spatial arrangements of these self-assembled nanoparticles can be potentially used to build increasingly complex structures leading to a wide variety of materials that can be used for different purposes." https://lnkd.in/dYubWQd View in LinkedIn

THERMODYNAMIC DRIVER OF SELF-ASSEMBLY. "Self-assembly is an equilibrium process where the assembled components are in equilibrium with the individual components. Self-assembly is driven by the minimization of Gibbs free energy." https://lnkd.in/dYubWQd View in LinkedIn

SELF-ASSEMBLY AND FREE ENERGY. "The minimization of Gibbs free energy is attained by the minimization of repulsive and the maximization of attractive molecular interactions. In addition, the lower free energy is usually a result of a weaker intermolecular force between self-assembled moieties and is essentially enthalpic in nature." https://lnkd.in/dYubWQd View in LinkedIn

THANK YOU ALL for the birthday wishes. Spent, in part, in the Sahara desert in a Berber Nomad tent after arrival on camels. Impressive people. View in LinkedIn

PROOF-READING IN BIOLOGICAL SYSTEMS. "The low overall rate of mutation during DNA replication (1 base pair change in one billion base pairs per replication cycle) does not reflect the true number of errors that take place during the replication process. The number is kept so low by a proof-reading system that checks newly synthesized DNA for errors and corrects them when they are found." https://lnkd.in/dFiK8bb View in LinkedIn

FIXING ERRORS POST-PRODUCTION. "After DNA has been completely replicated, the daughter strand is often not a perfect copy of the parent strand it came from. Mutations during replication and damage after replication make it necessary for there to be a repair system to fix any errors in newly synthesized DNA." https://lnkd.in/dFiK8bb View in LinkedIn