Year: 2022

ANTAGONIST DRUGS. "Elevated local or systemic IL-1β has been linked to a number of human hereditary or acquired diseases, and antagonists of IL-1β or its receptor are proving successful treatments for a number of these diseases. Clinical trials are currently assessing efficacy of Anakinra and next-generation IL-1β inhibitors for a wider range of diseases, including cryopyrin-associated periodic syndromes (CAPS), gout, and type II diabetes." http://www.sciencedirect.com/science/article/pii/S0092867410000759 View in LinkedIn

SO ENDS this fragment from nature on the remarkable inflammasome, and on the defense mechanism inflammation, which can sometimes be hijacked by pathogens, or go awry and cause diseases. Powerful remedies need stringent controls. Inflammation is at the root of many pathologies, and despite complex controls, can still cause self-damage. View in LinkedIn

GENES FROM FOOD. "Following ingestion by mice, DNA from the M13 bacteriophage could be detected as relatively long fragments in fæces, peripheral leukocytes, spleen and liver cells in significant time intervals after feeding. In the cells, the ingested M13 DNA was found in a chromosome-integrated form." https://lnkd.in/eJ8cwgX View in LinkedIn

HOT TOPIC. Whenever a firestorm of dissent breaks out about a scientific topic, one wise thing to do is to consider whose powerful toes are being stepped upon, particularly industrial toes. Sponsored disinformation attacks are a sadly common modern event. There is a long history of this going back to fluoride, tobacco, nutrition, and in recent years, GMOs. No longer a scientific debate, but an avalanche of the attack dogs. View in LinkedIn

FIRESTORM after the food genes to blood article from the pro-GMO sector. No surprises. https://lnkd.in/ePyzwUG View in LinkedIn

REFUTED RESULTS of food to blood study published in 2015. https://lnkd.in/eZfneK2 View in LinkedIn

UNKNOWN. "Prior to this year, governments concluded that transfer of DNA from GM crops/foods is unlikely to occur. Now we can see that they are wrong, or perhaps they had knowledge of this already? Regardless of the fact that DNA from GM foods can be transferred to humans and animals, very little is still known today and what is known does not look good." https://lnkd.in/ez2_YTV View in LinkedIn

GENE UPTAKE FROM FOOD. "Dogmas concerning absence of hazards have often been proven wrong (e.g. the Titanic). A relevant example is the belief that DNA in food and forage cannot be taken up from the gastrointestinal tract. This belief was supported by some experimental studies, and the whole evolutionary history as well as our daily intake of vast amounts of DNA from various sources goes to prove it." Or, you are what you eat? https://lnkd.in/eJ8cwgX View in LinkedIn

GLOBAL GENETIC MARKETPLACE. "Our bodies are a global marketplace where bacteria trade genes. For example, the gut bacteria of Japanese people have a gene that helps them to digest seaweed. They borrowed it from an oceanic species that hitched its way into Japanese bowels, aboard uncooked pieces of sushi." https://lnkd.in/etuiYJg View in LinkedIn

"MICRO-RNAs are evolutionarily conserved small non-coding RNAs consisting of on average 22 nucleotides. They mediate post-transcriptional changes in gene expression usually through binding to the 3′ untranslated region (3′UTR) of target mRNAs with their seed region." https://lnkd.in/erkHGt5 View in LinkedIn