BYZANTINE REGULATION. “Upstream cue(s) aside, the regulation of POP-1 asymmetry and binary specification in C. elegans seems byzantine. Indeed, nematodes are the only animal phylum with multiple β-catenin genes, and the nematode β-catenins are extremely diverged in amino acid sequence; most animal genomes encode a single β-catenin, although vertebrates encode one additional β-catenin homolog called plakoglobin.”
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