CANDIDATE GENES EMERGE. “In the largest linkage scan thus far performed for human familial longevity, we confirm that the APOE locus is a longevity gene and that additional longevity loci may be identified at 14q11.2, 17q12-q22, and 19p13.3-p13.11. As the latter linkage results are not explained by common variants, we suggest that rare variants play an important role in human familial longevity.” (APOE is a class of fat metabolizing pathway proteins linked to Alzheimer’s).
http://onlinelibrary.wiley.com/doi/10.1111/acel.12039/full
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022