TRANSCRIPTION FACTOR CANDIDATES. “FoxO transcription factors promote longevity across taxa. How they do so is poorly understood. In contrast to previous studies suggesting that DAF-16F plays a more prominent role in life span control than DAF-16A, isoform-specific daf-16/FoxO mutant phenotypes and whole transcriptome profiling revealed a predominant role for DAF-16A over DAF-16F in life span control, stress resistance, and target gene regulation.”
https://lnkd.in/eP_v6ZE
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022