HOMOPLASTY VS HETROPLASTY. “A mammalian cell has a single nucleus which contains a single genome. The genomic DNA is identical across all cells in an organism. A mammalian cell has many mitochondria and every mitochondria has its own (circular) genome. All the many individual copies of mtDNA exist independently of each other. If all the mtDNA in a cell are identical, then they are homoplasmic. (Common, “normal” situation). If one (or more) of the mtDNA in a single cell acquires a mutation, then the cell will have a mix of mutant-mtDNA and WT-mtDNA. These cells are now heteroplasmic.”
https://lnkd.in/eeWUxj8
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022