EXCESSIVE REDUNDANCY. “Knockout experiments do not necessarily give a good readout of the functionality of that protein or gene. In yeast knockouts up to 80% of the genes are silent, and that does not mean that they do not have physiological functions. The system is so well backed up that other networks take over the function of the knocked out gene.”
https://lnkd.in/eBKWC7d
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022