SO ENDS this first weekend on the theme of viral dark matter. Physics is thwarted by the presence of a majority of the physical world being unknown dark matter. So with biology. But in the case of biology, we have adopted an ostrich pose to account for our ignorance, with an early focus only on disease, and a persistent and willful attitude that these are non-living (and thus irrelevant) entities. A few pioneers are trying to pull biologists out of the Dark Ages.