MOST COMMON BIOLOGICAL STRUCTURE. “A protein fold that may be the most abundant biological structure on Earth. Surprisingly, the majority (67%) of the metaproteomic spectra were derived from just five environmentally dominant PCs. With a combination of sequence- and structural modeling-based annotation, these PCs are now predominantly identified as putative capsid proteins of tailed viruses containing the most abundant biological structure on Earth, the HK97-like protein fold.” (PC = protein cluster).
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