linkedin post 2017-07-03 03:44:28

DISCRIMINATION LACKING. “One ultimate goal of genomics is to read the code—to be able to predict variation in gene expression levels based on the nucleotide sequence—and this goal remains challenging. The main difficulty is that many changes in TF binding do not seem to result in measurable changes in gene expression levels, and we do not yet know how to distinguish between binding events that affect gene expression and those that do not.” (TF = transcription factor).

https://lnkd.in/dFv6Tsi

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