linkedin post 2017-05-22 05:09:26

EXPRESSION FIRST. “Through the acquisition of new mutations, proto genes can grow and result in functional de novo genes. Alternatively, it is also possible that the full-length transcript is initially interrupted by stop codons, but new mutations generate the full-length ORF of the de novo gene. This model is strongly supported by a range of studies that found transcription preceded the emergence of an ORF and translation.” (ORF = open reading frame).

http://www.sciencedirect.com/science/article/pii/S0168952515000347

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