TRANSCRIPTION HUB. “The complex, which consists of ∼30 polypeptides, shows conservation from yeast to humans and plays an indispensable role in regulating transcription. it soon emerged that multiple pathways responsible for cell growth, differentiation or tissue development were able to converge on one or more of the almost 30 subunits of Mediator through transcriptional regulators, suggesting that Mediator acts as a centralized ‘hub’ or ‘integrator’ for transcriptional regulation.”
https://lnkd.in/ez4iBiB
linkedin post 2022-06-29 05:12:48
Nigel Fleming
September 21, 2022