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"EPIGENETICS appears to be the return of the repressed of twentieth-century mainstream biological views of heredity." https://lnkd.in/dHbHGmK View in LinkedIn

DOGMA OF UNIDIRECTIONALITY. "The restricted or hard view of inheritance (i.e. impermeable to environmental inputs) that culminated in the central dogma of molecular biology (information can never go back from protein to DNA) acted like a cork that kept many alternative and unconventional views in the bottle of heredity." https://lnkd.in/dHbHGmK View in LinkedIn

OVERSHADOWED BY HARD HEREDITY. "Epigenetics possesses a unique heuristic value in bringing back to center stage views that were buried in the twentieth century by the triumph of hard-heredity and the exclusion of non-Mendelian forms of inheritance. And this historical and diachronic reading of epigenetics has implications also on the present, synchronic level, that is, the global, non-Western reverberations of epigenetics." https://lnkd.in/dHbHGmK View in LinkedIn

HERETICAL. "I refer to the cultural and historical significance of epigenetics for the century-long struggle about what counts as inheritance in evolution...epigenetics, understood as the culmination of a heretic line in the history of biology, and the history of inheritance in particular, uncovers forgotten, marginal, and even disgraced traditions in biological thought." https://lnkd.in/dHbHGmK View in LinkedIn

"CHALLENGE to the central dogma of molecular biology: epigenetics." https://lnkd.in/dHbHGmK View in LinkedIn

ONCOGENESIS. "Transcripts of noncoding genome revealed new dimension of the molecular architecture of cancer and lncRNAs are involved in all stages of oncogenesis. Gene expression profiles analysis of various tumors showed that lncRNAs are deregulated and functional studies have demonstrated that lncRNAs are implicated in general mechanisms of carcinogenesis." (lncRNA = long non-coding RNA). https://lnkd.in/d2sxUZQ View in LinkedIn

THE EVOLUTION OF SELFING. “Selfing has evolved in animals, fungi, and plants, and since Darwin's pioneering study, it is considered one of the most frequent evolutionary trends in flowering plants. Generally, the evolution of selfing is characterized by a loss of self-incompatibility, the selfing syndrome, and changes in genome-wide polymorphism patterns.” https://lnkd.in/dgPt-cE View in LinkedIn

SELFING. A comprehensive primer. https://lnkd.in/d9-MsRr View in LinkedIn

DISTINCT STRUCTURES AND PROCESSES. "However, in plants, clonal growth and selfing result from entirely different structures and processes, and the selective forces responsible for their respective origins and maintenance are quite distinct." http://www.pnas.org/content/112/29/8859.full View in LinkedIn

DISTINCTION. "Because clonal growth does not involve sexual reproduction, botanists make a clear distinction between predominant self-fertilization and clonal reproduction, a separation that is not as evident in the literature involving some other groups: e.g., fungi and parasitic protozoa. Both forms of uniparental reproduction limit recombination and can result in similar signatures of population genetic structure." http://www.pnas.org/content/112/29/8859.full View in LinkedIn