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SELECTION FAVORED. "Sex chromosomes can evolve in several different ways, and that recombination suppression is favoured when genes are involved that interact with sex with respect to their effects on fitness." https://lnkd.in/gCh5RAX View in LinkedIn

SUPPRESSION. "In addition to the creation of linkage between genes that were formerly on separate chromosomes, such rearrangements often reduce or suppress crossing over in the regions around the breakpoints in heterozygotes with the standard arrangement." http://www.nature.com/hdy/journal/v95/n2/full/6800697a.html View in LinkedIn

SELECTION FAVORED. "Sex chromosomes can evolve in several different ways, and that recombination suppression is favoured when genes are involved that interact with sex with respect to their effects on fitness." https://lnkd.in/gCh5RAX View in LinkedIn

FAVORED LINKAGE. "Translocations or centric fusions involving an autosome and a sex chromosome could also create linkage between sexually antagonistic genes and the sex chromosomes, and hence be favoured by natural selection." http://www.nature.com/hdy/journal/v95/n2/full/6800697a.html View in LinkedIn

RECOMBINATION SUPPRESSION. "The fact that this evolutionary change occurs repeatedly suggests that recombination suppression between the sex chromosomes was actively favoured by selection, rather than being a consequence of rearrangements such as occasionally occur on all chromosomes." http://www.nature.com/hdy/journal/v95/n2/full/6800697a.html View in LinkedIn

NO RECOMBINATION OF SEX CHROMOSOMES. "Whatever the mechanism, loss of X–Y recombination has occurred in different taxa, including repeated events in different fairly closely related lineages of birds and insects (Drosophila and mosquitoes, which have different sex chromosome gene content." http://www.nature.com/hdy/journal/v95/n2/full/6800697a.html View in LinkedIn

STEPWISE EVOLUTION. "Throughout mammalian evolution, recombination between the two sex chromosomes was suppressed in a stepwise manner. It is thought that the suppression of recombination led to an accumulation of deleterious mutations and frequent genomic rearrangements on the Y chromosome." https://lnkd.in/d5x7tBt View in LinkedIn

SPREAD BY CREEP. "Can recombination decrease without chromosome rearrangements, just by spread of recombination modifiers with small effects?" http://www.nature.com/hdy/journal/v95/n2/full/6800697a.html View in LinkedIn

GRADUAL OR DISCONTINUOUS. "Was recombination suppression in mammals a discontinuous process (due to successive inversions or translocations), or did it evolve gradually?" http://www.nature.com/hdy/journal/v95/n2/full/6800697a.html View in LinkedIn

NO CROSSOVER. "There is now evidence from several taxa (mammal, birds and plants) for more than a single event of cessation of recombination between X and Y chromosomes. The extent of DNA sequence divergence between homologous X/Y gene pairs of a single species has been found to vary greatly among genes, suggesting that different regions of the sex chromosomes have been nonrecombining for very different amounts of time, given that sequence divergence begins once crossing over between X and Y stops." http://www.nature.com/hdy/journal/v95/n2/full/6800697a.html View in LinkedIn