linkedin post 2018-01-08 14:11:29

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PARENT-OFFSPRING CONFLICTS. "Parents make decisions of allocations to offspring before the "meiotic veil of ignorance", whereas offspring compete for resources “from behind the veil”. These parent-offspring conflicts are likely at the origin of parental imprints that occur on some genes at or just before meiosis." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn
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linkedin post 2018-01-08 14:09:21

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GAMING TRANSPOSONS. "The second class of selfish genetic elements consists of meiotic drivers that exploit the asymmetry of female meiosis. These elements achieve transmission in excess of 50% by preferentially moving into the meiotic products that will eventually become the eggs or megaspores." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn
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linkedin post 2018-01-08 14:06:30

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CHEATING TRANSPOSONS. "These selfish genetic elements fall into two classes. Killer selfish genetic elements kill cells that have not inherited the element. In principle, such killers could operate during meiosis (the hypothetical ‘sister killers’ as discussed above), but the numerous killer selfish genetic elements that have so far been described operate postmeiotically, e.g. by killing sibling sperm." https://lnkd.in/e2tp_G5 View in LinkedIn
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linkedin post 2018-01-08 14:01:54

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GENETIC CHEATING. "A striking feature of meiosis is its apparent fairness: under Mendel’s first law of inheritance, each allele has a 50% chance of ending up in any given gamete. However, there are many selfish genetic elements that increase their chances above 50% by subverting the mechanism of meiosis." http://biorxiv.org/content/biorxiv/early/2016/04/28/050831.full.pdf View in LinkedIn
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linkedin post 2018-01-07 07:46:48

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SO ENDS this summary of Professor Denis Nobel’s thinking, as outlined in his book Dance to the Tune of Life. The central dogma of molecular biology was formulated by Francis Crick in 1958. Often stated as “DNA makes RNA and RNA makes protein”, in essence it states that once information gets into protein, it cannot get out again, and is unidirectional in flow, and information cannot flow from protein to protein or from protein to nucleic acid. Well, in the sixty years since this proposition, we have learned a lot, and the dogma has been modified. https://lnkd.in/eQDmUtj View in LinkedIn
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