linkedin post 2018-05-25 03:52:54
WHY LINEAR #1. "The earliest protoeukaryotes may have had only one or a few linear chromosomes encompassing the entire genome (which also necessitated the evolution of centromeres and telomeres to allow faithful segregation and protect the ends from decay). Linear chromosomes are required because crossing over between two circular chromosomes generates a circular dicentric that is unstable (the chromosome is broken if the two centromeres attach to opposite spindle microtubules)." http://cshperspectives.cshlp.org/content/6/3/a016154.full View in LinkedIn