linkedin post 2018-09-17 04:30:40

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SUICIDE BENEFITS GROUP. "Pea aphids (Acyrthosiphon pisum) that are parasitized by the Braconid wasp Aphidius ervi drop from the host plant, causing their own death. These insects live in groups of close kin, and their death prevents their body from producing parasites that would then attack their siblings. Death therefore increases the individual’s inclusive fitness, or equivalently, increases the fitness of the kin group." View in LinkedIn
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linkedin post 2018-09-17 04:26:35

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CONSENSUS AND EXCEPTIONS. "AP and disposable soma hypotheses are widely accepted as the standard explanations for genetic programs that cause senescence in multicellular organisms. However, there are some results that are in conflict with their predictions." (AP = antagonistic pleiotrophy hypothesis). View in LinkedIn
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linkedin post 2018-09-16 05:03:32

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SO ENDS this first of two weekends with Denis Nobel. Ideas evolve. In recent history, the genome was discovered. In short order, it was sequenced in many species. Then environmental influences were described. And with each step, our understanding of the meaning of the genome has changed. And will continue to do so as new findings occur. View in LinkedIn
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linkedin post 2018-09-16 04:58:37

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NO BLUEPRINT EXISTS. “Even when we add in the regulatory and non-coding regions, there is no program in the genome in the sense that the sequences could be parsed in the way in which we would analyse a computer program to work out what it is specifying. The reason is that crucial parts of the program are missing.” http://rsfs.royalsocietypublishing.org/content/2/1/55 View in LinkedIn
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linkedin post 2018-09-16 04:56:15

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KITCHEN OF TEMPLATE PLATTERS. “The protein-coding sequences are templates. They determine which set of proteins the organism has to play with, just as a child knows which pieces of Lego or Meccano she has available for construction. Those parts of the genome are best regarded as a database.” http://rsfs.royalsocietypublishing.org/content/2/1/55 View in LinkedIn
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linkedin post 2018-09-16 04:54:50

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CATHEDERAL ORGAN. “This metaphor has its limitations. There is no ‘organist’. The ‘music of life’ plays itself, rather as some musical ensembles perform without a conductor. And, of course, the ‘organ’ varies between individuals in a species.” http://rsfs.royalsocietypublishing.org/content/2/1/55 View in LinkedIn
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linkedin post 2018-09-16 04:53:14

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ABSURD PROPOSITION. “To think that the genome completely determines the organism is almost as absurd as thinking that the pipes in a large cathedral organ determine what the organist plays. Of course, it was the composer who did that in writing the score, and the organist himself who interprets it.” http://rsfs.royalsocietypublishing.org/content/2/1/55 View in LinkedIn
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