MISSING REFERENCE FOR TODAY. " "Are Internal, Death-Promoting Mechanisms Ever Adaptive?" "John W Pepper, Deborah E Shelton, Armin Rashidi and Pierre M Durand View in LinkedIn
EXAPTATIONS OF HOST GENES. "We suggest that the possible acquistion and retooling of intact eukaryotic-like domains in phage WO could be viewed as analogous to the commandeering of host genes by eukaryotic viruses. Whether lateral genetic transfers between metazoans and bacteriophages are common in the symbiotic virosphere remains to be determined." https://lnkd.in/dYh3-r4 View in LinkedIn
NEW GENE SHARING DOMAINS. "The findings here reveal the bacteriophage WO attachment and bacterial integration sites as well as evidence for gene sharing between metazoan hosts and phages of obligate intracellular bacteria." https://lnkd.in/dYh3-r4 View in LinkedIn
PHAGE SUCCESS. "Rather than simply act as virulence factors to benefit their bacterial host, their massive proportion of genomic real estate (up to 60% of the prophage genome) implies that they may be necessary to phage biology and likely have a direct impact on phage propagation." https://lnkd.in/dYh3-r4 View in LinkedIn
DEEP TOOLBOX. "EAM protein domains are prime candidates to aid in functions, including cell lysis (latrotoxin-CTD), manipulation of PCD (NACHT and NB-ARC), host ubiquitination (OTU and Ulp1), insecticidal toxicity (ABC toxin) and interaction with host proteins (ankryin repeats and TPRs)." (EAM = eukaryotic association module). https://lnkd.in/dYh3-r4 View in LinkedIn
BIRTH BALANCES DEATH. "Every second, several millions of cells of the human body undergo apoptosis, i.e. in conditions of homeostasis each mitosis is compensated by one event of apoptosis." http://mcb.berkeley.edu/courses/mcbc245/MCBC245PDFs/Jan31/Huettenbrenner2003.pdf View in LinkedIn
DAILY DEATH FOR HEALTH. "During embryonic development of the nervous system, the finger digits, or the ovary, but also in adult organisms, minutely regulated daily death processes maintain health and integrity." http://mcb.berkeley.edu/courses/mcbc245/MCBC245PDFs/Jan31/Huettenbrenner2003.pdf View in LinkedIn
TELOMERE REPLENISHMENT. "Even one-celled organisms count replications, and will die if they don't replenish their telomeres with conjugation (sex)." https://lnkd.in/dUX_Fna View in LinkedIn
PREREQUISITES. "Cell-death programs as prerequisites of organized life." http://mcb.berkeley.edu/courses/mcbc245/MCBC245PDFs/Jan31/Huettenbrenner2003.pdf View in LinkedIn