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REPLICON MODEL. "Imagine a molecule that likes its own shape: finding a copy of itself, it will fit neatly with its twin, forming for a while a complete entity. If the original molecule is presented with the component parts of itself, it will assemble these into additional replicas. The process will continue as long as the supply of components lasts." https://lnkd.in/dn83zJW View in LinkedIn

MOLECULAR REPLICATION. "We’ve published a body of work … where we’ve made small molecules that are capable of copying themselves...Just having a small molecule that replicates itself is not … ultimately very complex.’ https://lnkd.in/dDrKtFQ View in LinkedIn

"THE RNA WORLD HYPOTHESIS describes an early Earth with self-replicating and catalytic RNA but no DNA or proteins. It is generally accepted that current life on Earth descends from an RNA world, although RNA-based life may not have been the first life to exist." https://en.m.wikipedia.org/wiki/Abiogenesis View in LinkedIn

SUMMARY of self-replicating simple and complex molecules that make prions seem much more normal. Here are summaries of self-replicating systems including: hexadeoxynucleotides, RNA li gases, peptides, small molecules, ribozymes, micelles, prions and amyloid. https://lnkd.in/d6v_X9T View in LinkedIn

MOLECULAR REPLICATORS. "Autocatalysts are substances that catalyze the production of themselves and therefore are "molecular replicators." https://en.m.wikipedia.org/wiki/Abiogenesis View in LinkedIn

LIFE IN VENTS. “While features of self-organization and self-replication are often considered the hallmark of living systems, there are many instances of abiotic molecules exhibiting such characteristics under proper conditions. Stan Palasek showed that self-assembly of ribonucleic acid (RNA) molecules can occur spontaneously due to physical factors in hydrothermal vents." https://lnkd.in/dcd-YRj View in LinkedIn

ORIGIN OF LIFE. "An important open question is whether investigating such a random chemistry setting in the test tube is within the capabilities of current chemistry techniques. What is required is a capacity to handle the high number of molecular species, each potentially at low concentration, in very large volumes and for extremely long periods of time." http://www.weizmann.ac.il/molgen/Lancet/sites/molgen.Lancet/files/uploads/shenhav_lancet_core.pdf View in LinkedIn

BIOTRANSITION FROM THE INANIMATE. "The question "How does life arise from the nonliving?" is first on the list of open problems in artificial life." We do love this grey zone, it appears. https://scholar.google.es/scholar?start=50&q=artificial+chemistry&hl=en&as_sdt=0,5&as_vis=1 View in LinkedIn

ROTAXANE. "Scientists in the UK and Malaysia have created a self-assembling rotaxane that can replicate itself. The result may lead to the development of autonomous chemical systems that mimic cellular processes." http://www.rsc.org/chemistryworld/2015/11/self-replicating-assembly-rotaxane-dna-1 View in LinkedIn

SELF-REPLICATING MOLECULES. "He mentioned three specific groups of scientists, including his group, that have created self-replicating molecules, and indicated that there are others. I asked him if these were derived from naturally occurring self-replicating molecules, and he said that none of the molecules were derived from naturally occurring molecules." https://lnkd.in/d9-rKhE View in LinkedIn