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SHORTFALLS. "A Gemini spaceship is not a replicator, any more than a glider or other small spaceship is! A replicator is a pattern that makes copies of itself: the total number of copies of the pattern has to increase over time. If a pattern is "used up" in some way by the copying process, and is not capable of completing another cycle of replication after the first, then to be a true replicator it would have to produce two or more children simultaneously. Otherwise the pattern falls into some other category." https://lnkd.in/dNTQG9j View in LinkedIn

LARGE POPULATION. "Life enthusiasts have since catalogued an entire zoo of interesting patterns, such as “spaceships” that travel across the grid, or “guns”, which constantly spawn other patterns. But a pattern that spawned an identical copy of itself proved elusive." Too bad nomenclatures were not biological. https://lnkd.in/d5EF-mB View in LinkedIn

GREEN'S REPLICATOR. "Basically, it is the last step before an actual replicator pattern is built!" "Highlife-like replicators, here we come! I think the first "true" replicator will be built in about 2020. For the 50th anniversary of life" (Game of Life). https://lnkd.in/djU8N2U View in LinkedIn

FIRST REPLICATOR. "On November 23, 2013, Dave Greene built the first replicator in Conway's Game of Life that creates a complete copy of itself, including the instruction tape." https://lnkd.in/dzs-Kxk View in LinkedIn

SELF-CONSTRUCTING CIRCUITRY. "In 2010, something better did come along: Andrew Wade's Gemini spaceship magically appeared on the scene, and things suddenly got much easier for would-be replicator designers. Self-constructing circuitry was no longer just a theoretical possibility but an accomplished fact -- and the Gemini made it look downright easy." https://lnkd.in/dNTQG9j View in LinkedIn

CLOCK GENES. "Expression of the LHY and CCA1 mRNA levels oscillates and levels of both transcripts peak shortly after dawn. The LHY and CCA1 proteins also are synthesized rhythmically with a lag of approximately 2 h after their cognate mRNAs. Both transcription factors bind to a promoter element known as the evening element and act to inhibit transcription of evening-specific genes, including TOC1. In the evening, the level of both repressors declines and transcription of the TOC1 gene resumes." https://lnkd.in/d_f7kfY View in LinkedIn

POSSIBILITY OF LIFE TRANSITION. "Upon observing the seemingly unlimited complexity and variety of Life's evolving patterns, it becomes almost impossible to refrain from imagining, along with Conway, that, were the game really to be played on an infinite lattice, there must surely arise true living ‘life-forms’, perhaps themselves evolving into more complex, possibly sentient, ‘organisms’." https://lnkd.in/d3B2FKW View in LinkedIn

FEEDBACK LOOPS. "The circadian oscillator of higher plants comprises transcriptional– translational feedback loops similar to those described earlier for fungal and animal clocks." https://lnkd.in/d_f7kfY View in LinkedIn

CLOCK CENTRAL. "In plants, the circadian clock controls expression of approximately 6% of the transcriptome. This includes genes encoding components of all major metabolic pathways as well as genes involved in hormone biosynthesis, photoreceptors and floral regulators such as CO, FT and GI." https://lnkd.in/d_f7kfY View in LinkedIn

CLOCK GENE CO. "These results were consistent with a model in which expression of CO under the control of the circadian clock mediates rhythmic changes in photoresponsiveness and perception of external coincidence with light." https://lnkd.in/d_f7kfY View in LinkedIn