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DIVERSE SET. “The nematode Caenorhabditis elegans uses simple building blocks from primary metabolism and a strategy of modular assembly to build a great diversity of signaling molecules, the ascarosides, which function as a chemical language in this model organism.” https://lnkd.in/dHBmzX9 View in LinkedIn

PRESENT IN METAZOANS? “Considering that the various building blocks are highly conserved throughout the animal kingdom, it appears possible that similar strategies to create complex modular structures through combinatorial assembly of primary metabolites are not only prevalent among nematodes, but present in metazoans in general.” https://lnkd.in/d4DhYhz View in LinkedIn

LEGO SETS. “Our ongoing research also revealed that nematodes produce a large diversity of additional compounds by the combinatorial assembly of building blocks from primary and secondary metabolic pathways.” https://lnkd.in/d4DhYhz View in LinkedIn

WORD ORGANIZATION. “Ascarosides are organized in a very similar fashion, because they are all based on the dideoxy-sugar ascarylose and feature variations in the attached fatty-acid-derived side chain. Analogous to bacterial AHL signaling, different nematode species produce and respond to specific combinations of ascarosides. Based on recent findings describing modular assembly of ascaroside structures from a diverse array of biosynthetic building blocks, it is likely that many additional ascaroside structures exist in nematodes, perhaps also in species we analyzed in this study.” https://lnkd.in/d6G6mZ9 View in LinkedIn

BACTERIAL ANALOGY. “The conserved nature of ascaroside signaling is evocative of bacterial quorum sensing, where acyl homoserine lactones (AHLs) are both produced and sensed by many species of gram-negative bacteria. AHLs are based on a small invariable core structure, the homoserine lactone, which bears a fatty-acid-derived side chain featuring species-specific chemical modifications.” https://lnkd.in/d6G6mZ9 View in LinkedIn

THE PLAN. "The global internet is the planet for Project Tierra under open source volunteer projects. They may choose to migrate around the planet in the dark side where there is more CPU, which is borrowed at night." https://lnkd.in/d_8VqjV View in LinkedIn

LOOPHOLE. "In a typical developer’s environment the available de-bugging and disassembling tools are not perfect and have limitations that can be exploited by self-modifying code." https://lnkd.in/dHTSZ_H View in LinkedIn

THE QUESTION. "Can the evolutionary process develop that kind of software embedded in the digital world, in computers?" https://lnkd.in/d_8VqjV View in LinkedIn

GEEK TALK. "Evolution has produced massively parallel software with enormous complexity embedded in wetware." https://lnkd.in/d_8VqjV View in LinkedIn

CAMBRIAN EXPLOSION OF DIVERSITY. "Tierra creatures take resources (energy) and compete for computer time and computer memory, in order to reproduce themselves, and promote their survival. Tierra is a type of evolutionary process in a completely alien environment that can diversify like organic life had. It very quickly diversified and became very rich without any further help from Ray." https://lnkd.in/d_8VqjV View in LinkedIn