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KEY TO GREY ZONE. "It is only by clearly understanding how chemical systems can transfer and process information that we can hope to understand how self-replication and evolution can occur, and by implication, understand how life might have begun." https://lnkd.in/dhc7k7H View in LinkedIn

DNA MILIEU. "Natural selection does not operate on DNA only through organismal phenotype. Cells themselves are environments in which DNA sequences can replicate, mutate, and so evolve." https://lnkd.in/duMgVnm View in LinkedIn

INFORMATION. "This work suggests that the concept of a self-replicating chemistry is closely related to the concept of a chemistry that can store information and compute." https://lnkd.in/dhc7k7H View in LinkedIn

DNA FIRST PROPOSITION. "The assertion that organisms are simply DNA's way of producing more DNA has been made so often that it is hard to remember who made it first." https://lnkd.in/duMgVnm View in LinkedIn

CRYSTALLINE DNA. "I construct a chemical system that preliminary evidence suggests is capable of the most basic self-replication and evolution. The system uses no enzymes or biological sequences, can support and replicate a combinatorial genome, and is completely autonomous." https://lnkd.in/dhc7k7H View in LinkedIn

REVERSAL OF SPECIALIZATION. "Recently, however, a growing number of studies of specialization indicate that transitions from specialization to generalization are possible." https://lnkd.in/dcsE4uQ View in LinkedIn

NO EXAMPLES. "With the exception of biological organisms, we have no examples of self-replicating, evolving chemical systems." https://lnkd.in/dhc7k7H View in LinkedIn

REVERSIBLE POLYPLOIDY. "It is immediately apparent that polyploidy is, at least in part, reversible, and that over time it is followed by massive chromosomal rearrangements, reductions in chromosome number, and the large-scale loss of both repetitive sequences and duplicated genes all leading to genome downsizing." https://lnkd.in/eiPytFX View in LinkedIn

"TECHNOSPHERE was another pioneering artificial life project, with a population of 90,000 creatures." https://lnkd.in/dssAfsd View in LinkedIn

UNEXPECTED. "All of the behaviours described were exhibited by creatures of the order of thousands of instructions or less. By comparison, viruses also tend towards the thousands of instructions, although examples have been demonstrated that were less than 40 bytes. The actions that we normally associate with higher organisms may arise in viruses more easily than expected." https://lnkd.in/g5hUBjg View in LinkedIn