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EVOLVED UPTAKE. "The long-known existence of DNA uptake signal sequences and proteins that bind them, which jointly comprise a discrimination mechanism allowing bacteria to preferentially take up DNA from closely related organisms, is another piece of evidence in support of the view of transformation as an evolved route of gene transfer, apart from the nutritional value of DNA." https://lnkd.in/dSemZpD View in LinkedIn

EVE THE SCIENTIST. "Eve is a prototype system to demonstrate the automation of closed-loop learning in drug-screening and design. Eve's robotic system is capable of moderately high-throughput compound screening (greater than 10,000 compounds per day) and is designed to be flexible enough such that it can be rapidly re-configured to carry out a number of different biological assays." https://lnkd.in/dHmK73K View in LinkedIn

FRAGMENT FROM NATURE continues from last weekend and concludes this weekend on the theme of horizontal gene transfer. Although first described in the 1930s, it was not taken very seriously by biologists until about 1999, when it was increasingly realized that it played an important role in the evolution of many, if not all creatures. And that the main agents of this gene transfer were bacteria, jumping genes, and virus-like agents. Now it is accepted by the mainstream. https://lnkd.in/deYxkt5 View in LinkedIn

HYPOTHESIS TESTING. "Adam conceived 20 hypotheses concerning the identity of genes encoding 13 locally orphan enzymes in S. cerevisiae. Adam tested all these hypotheses on its robotic system and was able to confirm by experimentation, with a high degree of confidence, the correctness of 12 of them." https://lnkd.in/dHmK73K View in LinkedIn

"EVER WANTED TO have a robot to do your research for you? If you are a scientist, you have almost certainly had this dream. Now it’s a real option: Eureqa, a program that distills scientific laws from raw data, is freely available to researchers." https://lnkd.in/dEC3j_P View in LinkedIn

ADAM & EVE. "Towards Robot Scientists for autonomous scientific discovery. We describe our two prototype Robot Scientists: Adam and Eve. Adam has recently proven the potential of such systems by identifying twelve genes responsible for catalysing specific reactions in the metabolic pathways of the yeast Saccharomyces cerevisiae. This work has been formally recorded in great detail using logic." https://lnkd.in/dHmK73K View in LinkedIn

DOWNLOAD EUREQUA. https://lnkd.in/dxaxRNu View in LinkedIn

"ROBOT SCIENTISTS could provide a useful tool for managing such data and knowledge, making scientific procedures easier and more efficient. This kind of learning will become even more important as we move further towards integrative and predictive biology in the era of Web 2.0 and the Semantic Web." https://lnkd.in/dMfcK8Q View in LinkedIn

ABE ROBOT EXPERIMENTS. "In order to give ABE the ability to run experiments like Adam, Wikswo’s group is currently developing “laboratory-on-a-chip” technology that can be controlled by Eureqa. This will allow ABE to design and perform a wide variety of basic biology experiments. Their initial effort is focused on developing a microfluidics device that can test cell." metabolism.".” https://lnkd.in/eGii4i4 View in LinkedIn

BREAKTHROUGH MACHINE. "The research is being heralded as a potential breakthrough for science in the Petabyte Age, where computers try to find regularities in massive datasets that are too big and complex for the human mind and its standard computational tools." (Eurequa). https://lnkd.in/dEC3j_P View in LinkedIn