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DISTINCTION. "In many situations commonly accepted as SelfModifyingCode, the machine code being modified is a different part of the program than that doing the modifying." https://lnkd.in/dknBRJD View in LinkedIn

BYZANTINE REGULATION. "Upstream cue(s) aside, the regulation of POP-1 asymmetry and binary specification in C. elegans seems byzantine. Indeed, nematodes are the only animal phylum with multiple β-catenin genes, and the nematode β-catenins are extremely diverged in amino acid sequence; most animal genomes encode a single β-catenin, although vertebrates encode one additional β-catenin homolog called plakoglobin." https://lnkd.in/dAxynvD View in LinkedIn

PSEUDO SELF-MODIFYING. "For machine-code, SelfModifyingCode would be machine-code running on the CPU that reaches into its own in-memory or on-disk representation and tweaks that representation. And, even in the case of FPGAs and transmeta toolsets where you have a CPU that is modifiable, it generally isn't self modifying." https://lnkd.in/dknBRJD View in LinkedIn

REWIRING GENE REGULATION. "Our results suggest that promoter gain and loss is an important process in the evolutionary rewiring of gene regulation and may be a significant source of phenotypic diversification." https://lnkd.in/d6USApZ View in LinkedIn

"PROMOTOR TURNOVER has occurred at the majority (>56%) of protein-coding genes since humans and mice diverged. Tissue-restricted promoters are the most evolutionarily volatile where retrotransposition is an important, but not the sole source of innovation." https://lnkd.in/d6USApZ View in LinkedIn

GHOST IN THE MACHINE. "It is possible that soon we may be faced with an alien presence in our machines, a life that could combine aspects of the biological and computational world. Such organisms may be able to rewrite their own instructions, replicate at astounding rates or hide in storage for years. As electronic life moves out of a prebiotic stage, the rate of evolution may even accelerate exponentially, causing them rise towards and beyond us." https://lnkd.in/g5hUBjg View in LinkedIn

TRADE-OFF. "The majority of the new viral mutations are deleterious to the virus from a natural selection perspective. Was the high mutation rate of viruses a trade off for selection for faster replication rates? Faster replication rates afforded the ability to evolve more rapidly and adapt to new niches faster in bio-viral ecosystems.” https://lnkd.in/e9KGgbm View in LinkedIn

NO UPPER LIMIT OF VIRAL EVOLUTION. "What form these new lifeforms might take is unknown and perhaps unknowable, somewhat akin to trying to predict the shape of the modern world based on observation of the Pre-Cambrian era. Our experience with computational ecosystems shows no evidence that there is any upper limit on the complexity of electronic life given sufficient time." https://lnkd.in/g5hUBjg View in LinkedIn

SUPER-MUTATING VIRUS. "Not only does W95/Bistro itself mutate in new generations, it also mutates the code of its host by a randomly executed code-morphing routine. In this way, the virus might generate new worms and viruses. Moreover, the virus cannot be perfectly repaired because the entry-point code area of the application could be different. The code sequence at the entry point of the host application is mutated for a range 480 bytes long." https://lnkd.in/d_2z5qc View in LinkedIn

AUTOSCRIPTING SELF-MODIFYING. "Theoretically, there’s no reason we couldn’t create a Zajal program which would continue to mutate over a very long period, altering its own instructions as it runs and developing new behaviors." https://lnkd.in/dScXnfT View in LinkedIn