IMPLANTED MEMORIES. “The new work, published today in the journal Nature Neuroscience, shows for the first time that artificial memories can be implanted into the brains of sleeping animals.” https://www.theguardian.com/science/neurophilosophy/2015/mar/09/false-memories-implanted-into-the-brains-of-sleeping-mice View in LinkedIn
FRENCH MEMORY STUDY. "Explicit memory creation during sleep demonstrates a causal role of place cells in navigation. By triggering intracranial rewarding stimulations by place cell spikes during sleep, we induced an explicit memory trace, leading to a goal-directed behavior toward the place field.” https://lnkd.in/dKCe_Zr View in LinkedIn
FALSE MEMORIES. “Neuroscientists in France have implanted false memories into the brains of sleeping mice. Using electrodes to directly stimulate and record the activity of nerve cells, they created artificial associative memories that persisted while the animals snoozed and then influenced their behaviour when they awoke.” https://www.theguardian.com/science/neurophilosophy/2015/mar/09/false-memories-implanted-into-the-brains-of-sleeping-mice View in LinkedIn
INVASIVE PROOF OF CONCEPT. "Malinow believes that he has the potential to do something revolutionary: erase a memory or reactivate it at will. Optogenetics relies on the ability to insert a protein into nerve cells that will make them sensitive to light. Researchers can then activate the cells by exposing them to a light pulse: each time the light hits the cells, the nerve fires.” http://www.newyorker.com/science/maria-konnikova/can-memories-implanted-removed View in LinkedIn
IMPLANTING FALSE MEMORIES in a mouse. “Not only did these scientists identify the brain cells involved in encoding a single memory, but they also manipulated these cells to insert a false memory.” http://www.smithsonianmag.com/innovation/meet-two-scientists-who-implanted-false-memory-mouse-180953045/ View in LinkedIn
DEPRESSION AND ADDICTION. “Positive memory engram activation has recently been shown to alleviate stress-induced models of depression in mice. Furthermore, tagging and interfering with engram cells for cocaine-related memories has been reported as possible treatment avenues of drug addiction.” http://www.sciencedirect.com/science/article/pii/S0959438815001270 View in LinkedIn
ENGRAMS. “Manipulation of engram circuits presents many opportunities for significant practical applications. The efficacy of this technology for artificially updating existing memories, as well as for reversing the emotional valence associated with contextual memories, has been established.” http://www.sciencedirect.com/science/article/pii/S0959438815001270 View in LinkedIn
TRACE RECOVERY. “Memory engram storage and retrieval. Surprisingly, direct optogenetic activation of amnesic engram cells in mice resulted in successful retrieval of the ostensibly lost contextual fear memory.” https://lnkd.in/dkkp6td View in LinkedIn