linkedin post 2019-12-14 06:24:17

Uncategorized
ONE MILLION PROTEINS, 21K GENES. "One gene can encode more than one protein (even up to 1,000). The human genome contains about 21,000 protein-encoding genes, but the total number of proteins in human cells is estimated to be between 250,000 to one million." No longer the one gene, one protein dogma. https://lnkd.in/dKXbSw4 View in LinkedIn
Read More

linkedin post 2019-12-14 06:19:37

Uncategorized
FRAGMENT FROM NATURE deals with the genetic phenomenon called alternative splicing. By this mechanism, organisms can significantly amplify the number of proteins at their disposal, with a relatively small number of genes, thus making these new proteins available for adaptation and new functions. This illustrates how nature has arrived at an ingenious solution to generate, once again, the many from the few. View in LinkedIn
Read More

linkedin post 2019-12-13 06:49:21

Uncategorized
DURABLE IMPLANTS. “Two monkeys with brain implants have steered wheelchairs using only their minds, researchers said Thursday, in another step forward for a field seeking to mobilize people with paralysis. And the brain implants that made the mind-to-computer interface possible have lasted in the monkeys for seven years.” https://lnkd.in/dQvunCh View in LinkedIn
Read More
linkedin post 2019-12-13 06:46:28

linkedin post 2019-12-13 06:46:28

Uncategorized
MEDICAL USES. “BrainGate that allows fully paralyzed patients to control devices with their thoughts. BrainGate works by inserting a small chip, studded with about 100 needlelike wires—a high-tech brush—into the part of the neocortex controlling movement. These motor signals are fed to an external computer that decodes them and passes them along to external robotic devices.” http://www.wsj.com/articles/SB10001424052702304914904579435592981780528 View in LinkedIn
Read More
linkedin post 2019-12-15 05:09:59

linkedin post 2019-12-15 05:09:59

Uncategorized
PROTEIN AMPLIFICATION. "The proteins translated from alternatively spliced mRNAs will contain differences in their amino acid sequence and, often, in their biological functions. Notably, alternative splicing allows the human genome to direct the synthesis of many more proteins than would be expected from its 20,000 protein-coding genes." https://en.m.wikipedia.org/wiki/Alternative_splicing View in LinkedIn
Read More
linkedin post 2019-12-15 05:05:59

linkedin post 2019-12-15 05:05:59

Uncategorized
EXON SELECTIONS. "Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins. In this process, particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene." https://en.m.wikipedia.org/wiki/Alternative_splicing View in LinkedIn
Read More

linkedin post 2019-12-14 06:34:03

Uncategorized
RNA VARIABILITY. "Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from the surprisingly low number of human genes. Unlike promoter activity, which primarily regulates the amount of transcripts, alternative splicing changes the structure of transcripts and their encoded proteins." https://lnkd.in/dAwzAzi View in LinkedIn
Read More