21Sep 2022 by Nigel Fleming No Comments
linkedin post 2019-12-15 05:09:59

linkedin post 2019-12-15 05:09:59

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PROTEIN AMPLIFICATION. "The proteins translated from alternatively spliced mRNAs will contain differences in their amino acid sequence and, often, in their biological functions. Notably, alternative splicing allows the human genome to direct the synthesis of many more proteins than would be expected from its 20,000 protein-coding genes." https://en.m.wikipedia.org/wiki/Alternative_splicing View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments
linkedin post 2019-12-15 05:05:59

linkedin post 2019-12-15 05:05:59

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EXON SELECTIONS. "Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins. In this process, particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene." https://en.m.wikipedia.org/wiki/Alternative_splicing View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2019-12-14 06:34:03

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RNA VARIABILITY. "Alternative splicing is one of the most important mechanisms to generate a large number of mRNA and protein isoforms from the surprisingly low number of human genes. Unlike promoter activity, which primarily regulates the amount of transcripts, alternative splicing changes the structure of transcripts and their encoded proteins." https://lnkd.in/dAwzAzi View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2019-12-14 06:31:12

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VARIABLE RNA MESSAGE. "Changes in cutting and pasting alter the meaning of the document, often quite dramatically. Similarly, alternative splicing of RNA leads to a variety of possible mRNA isoforms and proteins, which can have different, and often opposing, functions." http://www.nature.com/scitable/topicpage/regulation-of-mrna-splicing-by-signal-transduction-14128469 View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2019-12-14 06:29:54

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FIXED DNA MESSAGE (NEARLY). "Genomic DNA is like a word-processing document that is "read-only" with no changes possible, whereas the RNA is a transcript of the document that permits, and even requires, cutting and pasting to get to the final version." http://www.nature.com/scitable/topicpage/regulation-of-mrna-splicing-by-signal-transduction-14128469 View in LinkedIn
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21Sep 2022 by Nigel Fleming No Comments

linkedin post 2019-12-14 06:28:26

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AMPLIFYING GENES. "Alternative splicing is one major mechanism that makes the most of the precursor messenger RNAs (pre-mRNAs) transcribed from these few genes by processing the pre-mRNA into a diverse array of mature mRNAs that encode distinct proteins." http://www.nature.com/scitable/topicpage/regulation-of-mrna-splicing-by-signal-transduction-14128469 View in LinkedIn
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