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ENORMOUS DIVERSITY. "Alternative splicing is a crucial mechanism for gene regulation and for generating proteomic diversity." https://lnkd.in/d5-PmqK View in LinkedIn

TWO WAY. “Connecting a machine so the human operator can access the functional capacity of the machine also allows the machine access to the functional capacity of the human.” https://lnkd.in/eB--UFz View in LinkedIn

TELEPATHY. “The distant “decoder rat” was taught by the neural traffic generated by the initial activity of the “encoder rat” and relayed by the direct brain-to-brain coupling afforded in this novel “artificial communication channel”. This shows that rats linked through brain-to-brain electrode arrays could learn complex, cooperative, goal-directed behaviors.” https://lnkd.in/eB--UFz View in LinkedIn

ELECTRIC TELEPATHY. “In this compelling research, two rats had electrode arrays implanted into the sensorimotor areas. One rat served as an “encoder” of sensorimotor information during performance of either a tactile or visual task. The cortical activity generated in the brain of the “encoder rat” was monitored and then relayed to a second “receiving” or “decoder” rat, located in a distant laboratory.” https://lnkd.in/eB--UFz View in LinkedIn

EXTENSION. “Brain-machine interface concepts could be extended to brain-to-brain interfaces for shared information processing.” https://lnkd.in/eB--UFz View in LinkedIn

RECOVERY OF LOST FUNCTION. “Herreros and colleagues successfully connected to the brain of an anesthetized rat as a “step toward the development of neuro-prostheses that could recover lost learning functions in animals and, in the longer term, humans”. https://lnkd.in/eB--UFz View in LinkedIn

CALIBRATION. “Bamford and colleagues used the known input and output properties of the cerebellum to guide the development of a prototype chip fabricated as a microcircuit. Real data from anaestethized animals were used calibration and training. The circuit could be “conditioned in a manner very similar to that of a real intact cerebellum” thus establishing partial brain function replication using BMI.” (BMI = brain machine interface). https://lnkd.in/eB--UFz View in LinkedIn

CLOSED LOOP DEVICES. “They envisaged engineering scenarios that could meet the challenge required for truly integrated neuroprosthetics—a closed loop system. Such a system would be able to send to and receive from the brain inputs and processing to control devices that supplement the functionality of the brain itself.” https://lnkd.in/eB--UFz View in LinkedIn

FINE TUNING. “This approach was extended to restoration of cognitive decision making using a neuroprosthetic interfaced into the prefrontal cortex in the rhesus monkey.” https://lnkd.in/eB--UFz View in LinkedIn

EARLY PROMISE. “Theodore Berger and colleagues who showed that an input/output (stimulation and recording) neuroprosthetic interface enhanced memory function subserved by the rodent hippocampus and could overcome memory deficits mimicking natural damage.” https://lnkd.in/eB--UFz View in LinkedIn