linkedin post 2021-05-29 03:32:50

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ALEXANDER RICH “had a long and fertile career at MIT working on the relationship between the molecular structure and the function of biological information molecules DNA and RNA. Rich is perhaps best known for the elucidation of the three-dimensional structure of a transfer RNA molecule, and for the discovery of an alternative form of DNA that exists in certain biological contexts, known as Z-DNA.” Charming photo. https://lnkd.in/d_NxPpN View in LinkedIn
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linkedin post 2021-05-30 05:32:38

linkedin post 2021-05-30 05:32:38

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TECHNICAL LIMITATION. “In the face of suggestions of this type, it was clear that the fiber diffraction studies with their limited information content could no longer be responsive to the question of what detailed conformations DNA is capable of accommodating.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
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linkedin post 2021-05-29 03:29:31

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FRAGMENT FROM NATURE this and next weekend features a 1982 article by Professor Alexander Rich of MIT on left-handed DNA, and how the early debate about DNA handedness was effectively resolved by better techniques. This is, in part, a historical note, in another part, a fresh look at the most influential molecule of the modern era of biochemistry. Fascinatingly, this textbook was published in typewriter font. https://lnkd.in/dadvE8B View in LinkedIn
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