linkedin post 2021-05-27 04:33:57
FOOTNOTE. “The total entropy of a system either increases or remains constant in any process; it never decreases.” https://lnkd.in/d_98ekG View in LinkedIn
linkedin post 2021-05-27 04:33:11
UNTHINKABLE VIOLATION. “In particular, to external observers it seems that the entropy of the visible universe decreases as the (entropy-bearing) object disappears into the black hole.” https://lnkd.in/d3sfhP6 View in LinkedIn
linkedin post 2021-05-29 03:32:50
ALEXANDER RICH “had a long and fertile career at MIT working on the relationship between the molecular structure and the function of biological information molecules DNA and RNA. Rich is perhaps best known for the elucidation of the three-dimensional structure of a transfer RNA molecule, and for the discovery of an alternative form of DNA that exists in certain biological contexts, known as Z-DNA.” Charming photo. https://lnkd.in/d_NxPpN View in LinkedIn
linkedin post 2021-05-30 05:32:38
TECHNICAL LIMITATION. “In the face of suggestions of this type, it was clear that the fiber diffraction studies with their limited information content could no longer be responsive to the question of what detailed conformations DNA is capable of accommodating.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
linkedin post 2021-05-29 03:29:31
FRAGMENT FROM NATURE this and next weekend features a 1982 article by Professor Alexander Rich of MIT on left-handed DNA, and how the early debate about DNA handedness was effectively resolved by better techniques. This is, in part, a historical note, in another part, a fresh look at the most influential molecule of the modern era of biochemistry. Fascinatingly, this textbook was published in typewriter font. https://lnkd.in/dadvE8B View in LinkedIn
linkedin post 2021-05-30 05:31:55
HYBRID. “Part of the stimulus came from the development of the idea that DNA might not exist as a continuously coiled double helix but that it might adopt a side-by-side conformation.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
linkedin post 2021-05-28 03:09:19
Montfalco Murallat, a door in the walled village. View in LinkedIn
linkedin post 2021-05-30 05:31:02
ALTERNATIVE FORMS. “It is only relatively recently that there has been increased emphasis on alternative conformational models for DNA.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn
linkedin post 2021-05-28 03:07:36
QUANTUM FROM PARTICLES TO STARS. “Quantum physics allows to make statements about the behavior of a wide variety of many-particle systems at the atomic level, from salt crystals to neutron stars.” https://lnkd.in/djnqdiw View in LinkedIn
linkedin post 2021-05-30 05:30:12
ELEPHANT IN THE ROOM. “Helical flexibility as a mechanism to either generate structural recognition signals along the DNA molecule or regulate superhelical topology was not discussed extensively.” https://link.springer.com/content/pdf/10.1007/978-94-009-7052-6.pdf View in LinkedIn